See below for registration details
The APGI and the Interreg 2 Seas project “Site Drug: Specifc Drug Delivery” (www.site-drug.org) are jointly organizing a “Hot Topic Day” dedicated to a highly challenging field of research and development: Local Controlled Drug Delivery.
The large majority of drug products available on the market deliver the drug in a non-targeted manner into the human body: The drug is circulated via the blood throughout the entire organism.
Parts of it reach the target site (e.g., a specific organ). However, the large majority of the administered drug dose is distributed within the rest of the body. Importantly, this drug is not only “lost” for the treatment, it is often harmful for the patient, causing potentially severe side effects.
The latter have 3 major consequences, they:
The aim of the “Site Drug” project is to develop innovative drug products, which are able to control the resulting drug distribution in the patient’s body: The drug amount at th site of action is optimized, and the amount that is “lost” into the rest of the human body is minimized.
The Hot Topic Day will be held in-person to allow for intensive exchanges. The scientific programme is as follows:
Parenteral Local Controlled Drug Delivery
A new understanding of drug release from PLGA-based drug delivery systems
Prof. Juergen Siepmann, University of Lille, France
Local periodontitis treatments: Formulation strategies and clinical aspects
Prof. Florence Siepmann and Dr. Kevimy Agossa, University of Lille, France
10:20-10:50 Coffee break
Oral Local Controlled Drug Delivery
Colon targeting: Opportunities and pitfalls
Prof. Abdul Basit, University College London, UK
Advanced in vitro drug release testing along the gastrointestinal tract
Dr. Frédéric Moens, ProDigest, Belgium
12:00-13:30 Lunch break
Advanced Characterization Methods: In vitro and in vivo
Cutting edge characterization techniques for local drug delivery systems
Prof. Axel Zeitler, University of Cambridge, UK
Zebra fish: An interesting in vivo model for drug product development
Prof. Jeroen Bussmann, University of Leiden, The Netherlands
14:40-15:10 Coffee break
Manufacturing of Local Drug Delivery Systems
The potential of 3D Printing for local controlled drug delivery
Dr. Alvaro Goyanes, FabRx, London, UK
An Engineering perspective on 3D printing of local drug delivery systems
Dr. Julian Apachitei, University of Delft, The Netherlands
Toward continuous manufacturing of local drug delivery systems
Prof. Chris Vervaet, University of Ghent, Belgium