Skin & Formulation,6th Symposium – Committee and Programme

Chairs of the conference 
  • Prof. Vincent Faivre, Paris-Saclay University 
  • Dr Anne-Marie Pensé-Lhéritier (HDR), President of FRMGalesens
Programme Committee
  • Dr Frédéric Bonté, Director of Scientific Communication, Guerlain
  • Prof. Laurence Coiffard, Nantes University
  • Prof. Vincent Faivre, Paris-Saclay University
  • Prof. Nicolas Huang, Paris-Saclay University
  • Dr Valérie Muguet, Project Manager, Galenic Formulation, Laboratoires Pierre Fabre, Division Medical Care
  • Dr Anne-Marie Pensé-Lhéritier (HDR), President of FRMGalesens

Monday 2 October

08:00Registration  
09:00Welcome speech  
 OPENING LECTURE NEW DIRECTION IN SKIN DELIVERY: FORMULATION
09:15

Prof. Marc Brown, Medpharm – UK

Risk mitigation in Topical Product Development:
Orthodoxy, Automation and Innovation

14:00

Xavier Ormancey, Laboratoires Pierre Fabre – France

“Controversial” excipients: strategy on substitution depending on
regulatory status

 SKIN BIOLOGY AND PATHOLOGIES14:35

Dr Laurianne Simon, University of Montpellier – France

Lipopolyoxazolines nanoformulations for improved skin delivery

10:00

Prof. Laurent Misery, CHU Brest – France

Sensitive skins: diagnosis and management

14:55

Mathis Benyaya, PhD Student, University of Lyon – France

Co-encapsulation of several actives in Pickering emulsions for topical delivery application

10:35

Dr Ecaterina Gore, Normandie University – France

Tactile Sensory Evaluation: an essential tool to evaluate skin-products interaction

15:15

Hishda Mohamed, SEDERMA – France

Several carrier systems to increase the benefits of active substances

10:55Posters session & exhibition – coffee break15:35Posters session & exhibition – coffee break
11:25

Dr Georgios Stamatas, Johnson & Johnson Beauté – France

Recent advances in skin maturation during infancy and childhood

16:15

Dr François-Xavier Legrand & Prof. Emilie Munnier

Deep Eutectic solvents for skin formulations

12:00

Dr Catarina Rosado, Universidade Lusofona – Portugal

Lipid-based nanocarriers on insect biomass to tackle atopic dermatitis

17:00

Christoph Heuberger, Lipoïd – Switzerland

Effects of Phospholipids on Skin Retetion and Penetration

12:20

Shimran Chaurasia, PhD Student, Maharaja Ranjit Singh Punjab Technical University – India

Design and development of Nano-carrier Based Bilayer Therapeutics System for Ungual Drug Delivery

  
12:40Posters session & exhibition – lunch break  

19:30 GALA RECEPTION

Tuesday 3 October

 

08:15Door opening  
 STRATEGIES OF FORMULATION NEW DIRECTION IN SKIN DELIVERY: TECHNOLOGIES
08:45

Dr Joana Marques Marto, University of Lisbon – Portugal

Waterless formulation in skin research

13:45

Dr Morgan Dos Santos, LabSkin Creations – France

Advances and Innovations of 3D Bioprinting Skin for the          
Performance Evaluation of Cosmetic Products

09:20

Dr Melanie Köllmer, RADES – Germany

Preservation of topical formulations: requirements and strategies

14:20

Prof. Ryan Donnelly, Queen’s College Belfast – UK

Micro-needles and skin applications, new developments

09:55

Prof. Guoping Lian, University of Surrey – UK

An end-to-end in-silico simulation workflow to understanding the formulation effect on perrcutaneous absorption

14:55

Paraskevi Kyriaki Monou, PhD Student, University of Thessaloniki – Greece

Fabrication of 3D printed coated microneedles with electrosprayed containing rivastigmine and N-acetyl cysteine nanoparticles for combined transdermal delivery

10:15Posters sessions & exhibition – coffee break15:15

Dr Franciska Erdö, Pazmany Peter Catholic University – Hungary

Raman spectroscopy in skin research

10:45

Dr Pascale Gauthier, Auvergne University – France

Packaging as a full partner for protect formulations

15:50

Lucas Chiarentin, PhD Student, University of Coimbra – Portugal

Towards the development and optimization of a rheology method for a high viscosity cream: An Analytical Quality by Design (AQbD) approach

11:20

Lara Gorsek, Student, University of Ljubljana – Slovenia

Biomechanical Properties of Sepigel with Flurbiprofen loaded Nanoparticles in vivo

16:10

Dr Katy Margulis, The Hebrew University of Jerusalem – Israël

Mass-Spectrometry Imaging-Guided Design of Dermal Delivery Systems

11:40

Benjamin Gavinet, Seppic – France

Topical formulation of high concentration of cationic-form lidocaine hydrochloride with anionic rheology modifiers

16:30Conclusion
12:00

Yvonne Wiedemann, PhD Student, University of Tuebingen – Germany

Poly(vinyl alcohol) Based Cryogel Patches as Drug Delivery Systems for Topical Application

  
12:20Posters session & exhibition – lunch break  

 

Invited speakers

Prof. Marc Brown BSc PhD, CChem FRSC, Professor

Prof. Marc Brown co-founded MedPharm in August 1999  and he  has been the guiding force behind MedPharm’s scientific developments and intellectual property since its inception. He currently acts as Board Director and Chair of MedPharm’s Scientific Advisory Committee.  Prior to MedPharm he was an academic in the Pharmacy Departments at King’s College London (KCL) and the University of Hertfordshire. He retains honorary and visiting Professorships at the University of Reading, KCL, and De Montford University and in 2022 was awarded the status of Professor Emeritus of the University of Hertfordshire. He has over 200 publications and 26 patents describing his work. His research interests lie mainly in drug delivery to the skin, nail and airways and to date, he has been involved in the pharmaceutical development of over 55 products that are now on the market in Europe, America and Japan.

Prof. Ryan Donnelly, Queen’s University Belfast

Professor Ryan Donnelly holds the Chair in Pharmaceutical Technology at Queen’s University Belfast and is Director of QUB’s interdisciplinary research programme Materials & Advanced Technologies for Healthcare (MATCH). His personal research is centred on design and physicochemical characterisation of advanced polymeric drug delivery systems for transdermal and intradermal drug delivery, with a strong emphasis on improving patient outcomes. He is currently developing a range of novel microneedle technologies through independent research, but also in collaboration with several major pharma partners. He has obtained substantial UK Research Council, charity and industrial funding and authored over 600 peer-reviewed publications (H-index = 76), including 6 patent applications, 6 textbooks, 23 book chapters and approximately 300 full papers. He has been an invited speaker at numerous national and international conferences.
Professor Donnelly is Europe/Africa Editor of Drug Delivery & Translational Research and a member of the Editorial Board of the Journal of Controlled Release. He has won Visit Belfast’s Ambassador Award for Life & Heath Sciences (2022), the Academy of Pharmaceutical Science”s Innovative Science Award (2020), the Controlled Release Society’s Young Investigator Award (2016), BBSRC Innovator of the Year (2013), the American Association of Pharmaceutical Scientists Pharmaceutical Research Meritorious Manuscript Award (203&2022), the GSK Emerging Scientist Award (2012) and the Royal Pharmaceutical Society’s Science Award (2011).

Morgan DOS SANTOS, PhD, General Manager and Chief Scientific Officer of LabSkin Creations

Morgan DOS SANTOS is currently General Manager and Chief Scientific Officer of LabSkin Creations, a biotech company specialized in advanced tissue engineering and dedicated to the testing of cosmetics and pharmaceutical products on in vitro skin models.
With a PhD in molecular and Cellular biology from Lyon University, France, Morgan has been developing for the past 20 years a high expertise in skin tissue engineering and 3D bioprinting. Originally trained in Edouard Herriot Hospital, one the the largest burn repair centre in Europe, he then moved to the cosmetics industry in which he actively contributed to the development of disruptive innovations in the field of skin bioengineering and skin care actives for dermatological and cosmetics applications.
After 7 years in China, working on skin fundamental research to transform disruptive science into innovation and new cosmetics product adapted to Asian consumers, he co-founded 2 biotech start-up companies in the field of personal care testing and regenerative medicine, LabSkin Creations and HealShape.
Morgan is author or co-author of many peer-reviewed journal papers and book chapters in the fields of tissue engineering and regenerative medicine, and he is also the co-inventor of PCT patents in bioprinting, epigenetics and active ingredients.

Franciska Erdő, PhD
Faculty of Information Technology and Bionics
Pázmány Péter Catholic University

Dr. Franciska Erdő has a PhD degree in pharmacy and pharmacology. She was working for research institutes in Germany (Max Planck Institute for Neurological Research, Cologne and Charité University, Berlin) and in Hungary (BIOREX Ltd, Veszprém and IVAX Drug Research Institute, Budapest) for several years. She has experience also from pharmaceutical industry (Sanofi-Synthelabo-Chinoin and SOLVO Biotechnology). Her previous projects focussed on the analysis of pathophysiology of stroke, blood-brain barrier and development new therapeutic strategies. Since 2014 she has been working for Pázmány Péter Chatholic University, Budapest as an associate professor and as a labhead. She moved to dermatology and cosmeto-scientific research fields. Her main expertise is drug delivery across the physiological barriers (dermal barrier, nasal barrier, blood-brain barrier etc.). Currently she is involved in a collaborative research on skin analysis and RAMAN spectroscopy with University of Tours, France. Also she is the supervisor of PhD, MSc and BSc students. She is the author of more than 70 scientific papers and several book chapters and editor of books.

Dr Pascale Gauthier, Pharmacist, PhD, lecturer,  Auvergne University

Pascale Gauthier is a Pharmacist (PharmD) with a research background: Biopharmaceutical Master (DEU) ‘New gelling process for oils, study of manufacture of sun care oleogels’, specific Master in Pharmacokinetic (DEA) Pharmacokinetic study of antihypertensive drug and its metabolites after single and repeated dose’ and PhD ‘Rotogranulation process used for manufacture of spheres.’  She was involved in several patents, international publications, conferences, Thesis and is judging for Pharmapack Awards (Exhibitors and Health products categories), CPhI (Excellence in Pharma various) and Design French Institute (Janus). Her researches focus on modified release forms, pharmaceutical design and categories of users, digital in health and beauty areas as well as innovative packaging and formulations for drug forms and cosmetics.

Dr. Melanie Köllmer, Co-Founder and Head of Formulation Development, RaDes

Dr. Melanie Köllmer is head of formulation development at RaDes. She has more than 10 years of experience in pharmaceutical and biomedical research. Her expertise lies in the implementation of development projects, from formulation design of semi-solid dosage forms in feasibility studies to clinical phase and process development.
She studied pharmacy at Phillips-University in Marburg, Germany, and received her PhD in drug delivery and tissue engineering from the University of Illinois at Chicago, USA, in the laboratory of Prof. Dr. Richard A. Gemeinhart, followed by a PostDoc at the Illinois Institute of Technology (IIT) in Prof. Dr. Eric Brey’s laboratory.
Subsequently, Melanie worked as a formulation scientist at Almirall Hermal, in close cooperation with analytical development as well as drug discovery, the IP and Regulatory Affairs departments, she worked extensively on the design of semi-solid formulations and the evaluation of new topical excipients and technology platforms. In particular, she made decisive contributions to the successful development of a stable aqueous tacrolimus cream (Patent WO201933722).
She foccuses on rational design, cosmetic optimization, and characterization of semi-solid formulations for small molecules and probiotics. A special focus is the use of modern rheological methods to optimize stability, manufacturing processes and user friendliness of formulations.
Melanie Köllmer is the author of currently nine publications in the field of drug delivery and in vitro performance testing and regulartly gives presentations in the field of formulation development and rheology.

Dr François-Xavier Legrand, Associate Professor, Paris-Saclay University

François-Xavier LEGRAND was born in Béthune (France) in 1984. He completed a Ph.D in Organic and Macromolecular Chemistry at the University of Artois in November 2010 under the direction of Professors Eric Monflier and Sébastien Tilloy. During his Ph.D. in the Catalysis and Solid Chemistry Unit, he worked on the development of novel cyclodextrin-based transporters and ligands for organometallic catalytic processes in aqueous media. He then obtained a Post-Doctoral Engineer-Researcher position in the Laboratory of Structure and Dynamics by NMR at the French Alternative Energies and Atomic Energy Commission in Saclay and worked on the interaction of gases with water-soluble cage molecules by nuclear magnetic resonance and gas hyperpolarization for NMR applications. In September 2011, he was appointed Associate Professor at Paris-Saclay University (formerly Paris-Sud) and joined the team Multiscale Physical Chemistry for Pharmaceutical Sciences (formerly Physico-Chemistry of Multiphasic Systems) at the Institut Galien Paris-Saclay. His current work is focused on the design and the characterization of complex supramolecular systems based on cyclodextrins and / or lipids with or without molecules of interest for drug delivery, especially for the treatment of acute myeloid leukemia. Since 2018, he has been interested in the effect of deep eutectic solvents on the skin for pharmaceutical and cosmetic applications as well as their use for the cutaneous delivery of therapeutic molecules. In this context, he was awarded a young researcher grant from the French National Agency for Research in 2019 to study the use of deep eutectic solvents for the treatment of cutaneous leishmaniasis. More recently, he has also focused on better understanding the behaviour of deep eutectic solvents after oral administration.

Dr Joana Marques Marto, PhD, Assistant Professor at Faculty of Pharmacy, University of Lisbon

Joana Marques Marto is currently an Assistant Professor at Faculty of Pharmacy, University of Lisbon. Since the beginning of her career, Joana Marto’s main research interests have been the development and characterization of drug delivery systems for topical application. Further, she always focused on transposing the fundamental research to the applied (market).

Prof. Laurent Misery, University of Brest

Professor of dermatology at the university of Brest, head of the department of dermatology of the university hospital of Brest, director of the french expert centre on pruritus, director of the laboratory interactions neurons-keratinocytes (LINK), chair holder of the partnership chair of neuro-sensory dermatology, author of more than 50 referenced papers on sensitive skin

Prof. Emilie Munnier, Faculty of Pharmacy of Tours

Emilie Munnier is a professor at the Faculty of Pharmacy of Tours where she has been teaching pharmaceutical technology and cosmetology for more than 10 years. She is also a researcher in the team EA6295 NMNS Nanomedicines and nanoprobes. After her Pharm degree, she obtained a PhD in Life and Health Sciences at the University of Tours dealing with nanotechnologies for health. Using her skills in formulation and analytical chemistry, she currently focuses on innovative formulation, among which the encapsulation of active molecules to improve their penetration into the skin, but also to control their interaction with the ingredients of a finished pharmaceutical or cosmetic product. She is also interested in the development of bioanalytical methods to measure the stability and the efficacy of cosmetic products. She has been coordinator of several research projects involving actors of the cosmetic industry, and is currently coordinating the ANR project DES4Skin dealing with the use of natural deep eutectic solvent (NaDES) as innovative ingredients for cosmetic products.

Xavier Ormancey, MSc, Laboratoires Pierre Fabre

Mr. Xavier Ormancey, MSc, is the Director of Research and Development for Pierre Fabre Dermo-Cosmetics and Personal Care. He has more than 35 years experience in the beauty industry in France and in USA (L’Oréal, Chanel, Yves Rocher, Beautycounter). As a specialist of natural cosmetics and clean beauty, he initiated the Conscious Care inception at Pierre Fabre, which enables the formulation of a new generation of dermo-cosmetic products safer and more efficient but also more committed and more respectful of resources and people.

Georgios Stamatas, PhD, Research Associate Director &Fellow, Translational Science, Johnson & Johnson Consumer Health

Dr Georgios Stamatas is a Biomedical Engineer with more than 20 years of international experience in Health Care industry. He is passionate about discovering actionable scientific insights, currently focusing on the understanding of skin physiology and the effects of topical skin care products. He is leading a scientific team pioneering work that ranges from microbiome and metabolome to computational biology and development on non-invasive clinical methods. This research has led to an important number of global “firsts” supporting the scientific credentials of Johnson & Johnson Consumer Health, including a paradigm shift in our knowledge of infant skin maturation and understanding the mechanisms of cutaneous adverse reactions during oncology therapy. Dr. Stamatas holds a PhD in Chemical/Biomedical Engineering and has co-authored more than 100 peer-review publications and 14 patents.